BIOAVAILABILITY AND SWALLOWABILITY OF AN AGE-APPROPRIATE, DELAYED-RELEASE MESALAMINE FORMULATION IN HEALTHY VOLUNTEERS

Bioavailability and swallowability of an age-appropriate, delayed-release mesalamine formulation in healthy volunteers

Abhijeet Jakate,1 Brian McNamee,2 Donald Burkindine31Clinical Pharmacology, Allergan plc, Madison, NJ, USA; 2Clinical Pharmacology, Allergan Biologics Ltd, Liverpool, UK; 3QPS Bio-Kinetic, Springfield, MO, USAObjective: Delayed-release mesalamine 400 mg capsules containing four 100 mg tablets have been developed for children with ulcerative colitis

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Biogeochemical Model Optimization by Using Satellite-Derived Phytoplankton Functional Type Data and BGC-Argo Observations in the Northern South China Sea

Marine biogeochemical models have been widely used to understand ecosystem dynamics and biogeochemical cycles.To resolve more processes, models typically increase in complexity, and require optimization of more parameters.Data assimilation is an essential tool for parameter optimization, which can reduce model uncertainty and improve model predicta

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